Pain Management (2014-17)
Migraine is the 3rd most prevalent illness in the world. There is an unmet clinical need to improve the treatment of migraine and develop novel treatment strategies to decrease the pain of acute migraine attacks with fewer adverse events than the current conventional medications.
Our research was helpful to advance the field by investigating potential agents for the management of acute migraine through a series of clinical trials.
Parkinson’s Disease (2015-19)
We conducted several systematic reviews and meta-analyses to study several interventions for Parkinson’s Disease, including the following categories:
- Neuroprotective and disease-modifying agents
- Add-on therapies
- Procedural interventions
This project resulted in about 20 publications.
Evidence-based Reviews (2014-now)
Since 2014, our team, Medical Research Group of Egypt (MRGE) has conducted more than 40 systematic reviews and meta-analyses to investigate several important research questions in all medical areas including but not limited to: Neurology, Cardiology, General Surgery, Infectious Diseases, Rheumatology, Dermatology, Hepatology, Hematology, and Oncology.
Until now, the MRGE team is actively working on several evidence reviews. My role is to mentor the research work methods and statistics and provide advice when needed.
Global Surgery (2014-20)
I worked on two global surgical collaborative projects. The first one was “GlobalSurg-1 project (2014-2016); Determining universal markers of quality in abdominal surgery: an international prospective cohort study” – which was published in the British Journal of Surgery. My role was as the national research coordinator in Egypt.
The second project was the Global PaedSurg-1 project (2018-2020): Management and Outcomes of Congenital Anomalies in Low-, Middle- and High-Income Countries – which was published in the Lancet. My role was the coordination of the study in North African countries.
Global NeuroSurg-1 (2018-now)
In 2018, I established the Global Neurosurg Research Collaborative with the help of my mentors Prof. Ahmed M. Raslan and Prof. Ahmed M. Hegazy.
The first project of the network (Global Neurosurg-1) aims to identify the current management pattern and outcomes of Traumatic Brain Injury in low-, middle-, and high-income countries. This project is ongoing until early 2022. In 2022, we are launching the Global Neurosurg-2 study on ……..?!
MRSClin Company (2018-now)
In 2018, I started the MRSClin company in partnership with my friend and co-worker (Dr. Hussien Ahmed). In MRSClin, we provide our customers with a wide array of professional clinical research services, including but not limited to statistical data analysis, scientific writing, protocol drafting, manuscript drafting, journal suggestions, proofreading, consensus guidelines development, literature reviewing, data management services, pre-publication peer-review, language editing and proofreading, and many other services.
COVID-19 MENA (2020-now)
In response to the COVID-19 pandemic, we created a multidisciplinary group of medical researchers to study the situation of COVID-19 in the Middle East and North Africa region. The team is named “COVID-19 MENA rapid response team”.
The team has conducted over 30 studies, many of which have now been published in international peer-reviewed journals. Many are still ongoing.
UK-COTS study (2020-21)
In response to the COVID-19 pandemic, the UKCOTS study was a multicenter observational study of the impact of COVID-19 on trauma surgery in the UK.
The study included more than 40 centers in the UK that provided data on the patterns of trauma surgery in 2019 and 2020 at the peak of the pandemic.
Global COST (2020-21)
This study was an international survey to determine the impact of the COVID-19 pandemic on surgical practice worldwide.
The study was registered in the COVID-19 research team of the Royal College of Surgeons in the UK. The manuscript was submitted and is currently in the peer-review process.
iROBOT surgeon survey (2020-21)
Robots in surgery can be more sensitive, more precise, can scan for problems a human may not see, and they can draw on data from procedures carried out by other robots. Robots do not get tired and their decision-making is consistent. But if they do make mistakes, who is responsible? This international survey, led by Aimun Jamjoom, Ammar Jamjoom, and Hani Murcus, provides five scenarios that are entirely fictitious. In them, a patient comes to harm and you need to judge who is most responsible. The study was completed and is currently pending publication.
Global Neurosurgery Special Issue (and e-book) in Frontiers (2020-now)
The primary goal of this Research Topic is to advocate for Global Neurosurgery as part of the Global Health spectrum that requires extensive efforts in the upcoming years to eliminate the existing health inequities and avoid preventable deaths in low- and middle-income countries. We also aim to highlight the current needs, capacity, efforts, and future directions in the area of Global Neurosurgery.
Stem Cells in Neurological Disorders (2020-now)
We are currently accepting submissions for the special issue entitled: “Stem Cell Transplantation Therapy in Neurological Disorders: Current Status and Future Directions” which will be published in the journal “Current Neuropharmacology” – Impact Factor = 7.3
Link: https://benthamscience.com/journals/current-neuropharmacology/special-issues/ (scroll down until you see the special issue title)
Journal of Global Neurosurgery (2021-now)
The journal of Global Neurosurgery (JGNS) was created by Dr. Kee B. Park (my supervisor at Harvard PGSSC), Dr. Andres Rubiano (owner of the Medtech foundation), and Dr. Ignatius Esene (chair of the Young African Neurosurgeons Society), with the aim of empowering researchers from low and middle-income countries (LMICs) and freely disseminate ideas and knowledge about global neurosurgical inequities and inform the path to universal access to neurosurgical care through quality scientific publishing.
I’m currently the Managing Editor of the JGNS and we are accepting submissions for many global neurosurgical areas: issue 2 for pediatric neurosurgery, issue 3 for cerebrovascular neurosurgery, issue 4 for Global Neurosurgery action plan, issue 5 for neurotrauma, … etc.
WFNS Global Neurosurgery Committee (2021-now)
The World Federation of Neurosurgical Societies created the Global Neurosurgery Committee to align and coordinate the global neurosurgery activities in order to foster collaborative and synergistic efforts.
I’m currently working in the WFNS GNC secretariat team. The WFNS GNC has >20 ongoing global neurosurgery projects. Neurosurgeons, trainees, and students who are interested in global neurosurgery can get involved.